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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edbd8bd30ef2c23b8a3ddd53b7dcce54d06a3596e46a3cfb816e19003ed5e6d8' 
  AND token = 'GM+SwG/IN92qri1MhU3QmB9GUq3njU8PvYhQ4T9wfA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}