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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a8154459aec642c3f90bff887263ad73e8e78b3aa946affa3d85dd0f14afc2' 
  AND token = '8DRDZ4h0Bw5/JP5ndt0Oor89LpWy0Y/qZF3KZsBnL7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}