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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a0c99d12c88b3bbf221f743a91a3f8ae460d2aa24c4d07f1ed2641139d84cb' 
  AND token = 'oLne6GXUd9sQTlgRhnpznYwDB8G0f2yPMPFce7e4VR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}