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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c16ab3c81c51753e631d6a4d6c8aee3528665d7455aac1a1e7c6c94e05e0c8b' 
  AND token = '53Apl+Kq3WlEf9SYt+G0AINkFknKH27YVbDmapRQn64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}