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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f466291af7a387ced762c440db66140b0e6415d9a567005293c0aa0f0b3a97' 
  AND token = 'RiL2XXFZBEMNitLXYEnfo3bHvxeSPKInluaJ+1cHi1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}