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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c2041422a103db58d817aa8947414b5606654834e99efd1fea1daf46c8c655' 
  AND token = 'giBPxRtE2krzm3iGvRpA5kTl8Yw7gKyLSyf4Qgle+sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}