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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c2dabdb115b46540bdfecf0543143dd55d96b7c33310da9d8f44f2eff879e8' 
  AND token = 'njFM0gKHyLUlOXffkZdFp+/pFpteLr8dCjGMvvVD1u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}