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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce34473ea2ffb10b18aad818318a86f47cd11bd59b3e26976ad7bbf097c1c375' 
  AND token = 'xtIhLRvcZ4cxcVU5ce+tjRdJJJSfeGBNf5QQP68mO6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}