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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f35ac1fb028f6628d4259b0dceed7205bbbc86a4bf8d8de97f45cfd7d0ab181' 
  AND token = 'xWXTc8dN8QN2yMcFIpj1qy2j/l57xkR/si8tWRnE+TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}