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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4558d3233e31369dd3beda2661f30cc69049a6a11888f8eb630ddada63c9b498' 
  AND token = 'sHYCpVAn/MWDjFi3Q+4OqrJ8pz5ZfM69LIvmh6idbwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}