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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e2cf5c8378d291133734b979ba73b709622310344f3d61b3ab8bd0cf29953b' 
  AND token = '5E9NncsfjZqX9SdXu6mrxUenedc93IQwpYHtQNSthDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}