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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2981699ba8cc3fe86818b299dc1f8a6e16039a0ec9d2bec6f98c8b6a223192' 
  AND token = 'zVa++0X4UVQVqdPB3RkXZdFcXM8f+IWZ4O2ZZEWvUoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}