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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514264b644c19e354937269d35352963e7426db0b1e3e98c13bb8fba96af2e60' 
  AND token = 'y53ZwH1kXK0V5b6/2FVPsccleLmnLWzvjsHAD/S+f4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}