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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2810d17ff1208bee6950e61ed8efa6d8dc43faefb8048a6f30072eaf0d8bbf' 
  AND token = 'I4IKTUjzytWtGIshmDp8/3WK4cpDAWax29+qwwhNQdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}