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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75953d679c063817a8510d9eabe1e01f8ac2740a5f7d48eda902a139c646fda3' 
  AND token = '8h5o8VlwoJxuDXz1zcN6haEnrIMtEact+yvW/9w0c98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}