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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee18b5c99b7c7914a5ebc23aabb91de1b4fa8d15f04f244b51d82e3f3cf0160d' 
  AND token = '5jDDUGw/GOXMIj5AT0LyC/X09O1amQO9qHKaXOZuu94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}