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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0457701d119127e2cd52beac6f100a70796c6ed1ce666bd876915f5dde6b764' 
  AND token = 'QaPy2sO4+izXZSvU+gTkLGJjhgr83sNKe1xqgayzLTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}