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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5e8ce01d8948c95b829491b86cdfc8db9574c19ebeb6bd151cc2f55e1de843' 
  AND token = '0oc1GZ2lo0DIzzgfdtPjnW47bqASOePwp7rT00Bf2oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}