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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a01f497b40d23e48b59861b90ff126fab94561d8cee748367a21db29114db5' 
  AND token = 'KA87l9HLppwUQi5D0AHLveOWVDyvvlB02NAiWi7eHAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}