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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40002f3abe5a76407d689158e58a74947cfd4ca82abe7e59eba19ac361b1ac38' 
  AND token = 'TVXiM+NTJp8akwxV9fRS3JtxbWtM1ukiNx2bHKouMSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}