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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1b9c65b95815171dd6ec2be6dbeb4c961b6c0a14abf8df2717e5591ba528d4' 
  AND token = 'wj7M+5g5HHd3zxe3k1OZzvfUAVfMcGuk3SmHdqkRZ40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}