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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b63c7d1a5fb3597fa79f68dd71705769af1e1e1a51143bf54fb4bef8ace5054' 
  AND token = 'o7Xoe4b18x1SeP7J6aD9tXrXcZuaEnXrF1c52xjYsRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}