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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c281b378fcb8c4cea14a9d8da416a17d10b9a6a12fdb1920268b1f0e55e2ca' 
  AND token = 'GsAdRvANpMjHBugqGGRgd3zQ9ye6KmocEv30SXGEoG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}