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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0ba131fd4361305fd4a9eeedb872e5647c080b8da6de4b4fb5d52676e7b214' 
  AND token = 'g0PnNVAjm9gvxD7vOazbHi3RVTyMFsPNOA4FubpICh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}