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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c72f12d5e9fba9fb67f9a176bff791a56a62d03e466464add3bec132dce4fb9' 
  AND token = 'vyypxSPtb6BIS3Qp4VBxyg2UAKyWBfbBODDxdg9wdUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00567

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}