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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21cbefc742e97725b1ce9f54557a11c6e20f2c1199c9328c69db9d519fb34013' 
  AND token = 'nUrp8sp9MVDzd9HM1DFf+AXNKGpx6RdWwmU8X80YBTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}