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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e8863945295ed4c08598af8a5451d57c419e855606f955ce74c3b29150bb91' 
  AND token = 'I1QbItEmeNWcv49/Vjq5P1ipXPHh7QZ6LOMl4WB2ngk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}