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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e963742153f906109cd834a9dee0ad0849cebd811f21f462d0c4b885813fb344' 
  AND token = '3vv1XAynkcD4fWl9pPyRGRokOXUkohg08QOgptaOuoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}