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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd4ff06dd4c885118c736d5d3f6fa7eecad71a973e1094f8d2f8821a1f2a44a' 
  AND token = 'MDruc2FXlhkJnj3R8RoazAFxQ0JLPPxF5ocUtaWRJIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}