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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cc5823bfee97f8a099e3cafe3641514e479f963d2a9ee9d2df925ccd9de225f' 
  AND token = 'CwjirywTHDM5OUw7f8udH5MPyaMb+IsFfcpFUHM79VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}