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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f4c343ab4f0ec576a8561a8156c575549ebe8b2fc7016e8b775680af86a716' 
  AND token = 'Yn+jXR2EOeqsZWltKZwmlN5+hTSRT3nGY9Y1ApHGHsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}