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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62d89a69b8e89c11bd24d1abb5bbc01eb5ad4bb544492a05b4e30365d0a69870' 
  AND token = 'iDBjhm/u2w17eOjTrmeQ6+dm1c9pzM1UbOQJJB4et9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}