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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa8a83b0d6db1b5a168ce640d285f92b3d5aee01ac28957c0ebde48f3ed065f' 
  AND token = 'vUMVTBrTb1UO3Ecl0jLe5xrk++meHZciyo09FGDwIbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}