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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16bf0c7a1535da0ebb2a827abbb04270e8665c4989d2e68c7f8e5c6c9688d08' 
  AND token = '9GoPC612C4rMJs+aC4BZk0SQUeKLij7qLqciR7wnxeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}