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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8496f247811597894502fc37397e1e284f49062c26bb2097e33e338757d76cf' 
  AND token = 'ZDeh5EQXNiXcIZFVuWo4UJCT+SzoZTS1MSlghRth7eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}