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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4c433bcb673713d7116e87d5c3c96c6e75ffb7d011cd51c093d2f0a05184ad' 
  AND token = 'bA29vaQfbXphqFxWWMDUXVDzWuGF3B32H8478eTjNKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}