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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86769e63379025eb21583e2982478c1b2d7600da2db9aebd9e3bf8bc71422568' 
  AND token = '6u0yVzXqLFtWA6T4vHjMhSm29uZMYa/oem1eMCognK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}