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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87d3924ed8952638dee505e130b2eb629888878211a74554b401180db6318b25' 
  AND token = 'AjM6Q8QvW0zRiG9AbCySMYdkwBi3uS1UbkXeseATCGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}