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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1945691fb61423aa46c20837505acb2c6b1a3e00c8e052816a8427db06c2db26' 
  AND token = 'XNe5w6PnXxhXvuaa8+GYSv8JYD1QpgpUdzFiVxurfzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}