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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378d984c7607a9dff55826579e682382ace3cefe86d581318c94ff0866f90a19' 
  AND token = 'ZTElhwiI4Pv1Ruz7YibZjoel6ZawkHF3dY2tGToKn0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}