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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff6cb8cd081d2e33ce04547c01d1b26a3f0157a9e6e6c24e19062f036f96c70' 
  AND token = 'i/YnpYYLwClDDv0iyxBd3/iEJYCixsv/z176SzkTSe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}