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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32af0d80ff62e158e562f1cf7e738f9794fd1f3b27978b11acf82588b3f8ebc' 
  AND token = 'vvk5D6020msXcnpSHOBuWHM+UD4M+3t2dv2NilgxSls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}