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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c426fa944db57ba80fd0ac401af5dfa280ee62a1cfef1ab60b0b760647944ef9' 
  AND token = 'O1646S74/357TvV4LYBiYIiB1iLBv7M5ZJgA+/gTLIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}