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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e09c1d251bf1b03d32c47f7db2db1e7394728113358a84a3deafffab6de5010' 
  AND token = 'qdX+oJvLqKzKsW35v9XnYtFgw3dQqkydIh6Y5NQdqXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}