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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd312ca5c9343a47fa09468f3bbe5a7a08d0b0fadb63ffec007563be4255a2c55' 
  AND token = 'qmJ4ry+8i0LLtBb+CKAiZd/NYhwgvW83N+EaiiMW+2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}