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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a38c2aa6a56802a9e6ed52124eefa947faf3b30e6002b45d8018b59c414269a' 
  AND token = 'fCE4PXRwxL7p2OclPULhPZycjIzHcnJQUGPWjSrr/3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}