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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81470dc7a60596c700dded3e149e776bb8208006d04ddb1787114c02a07ff544' 
  AND token = 'C1LbJ3wOA+sJ5GbfRhoPwu2vrKDTMM9g7fL0M2r60Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}