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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a50331879edce5083768b1e1180cbb5466e34cb535a96aba43b5b37075e92bf' 
  AND token = '4Y4+nfyz7RwMY4KLWmbBf9hreq97F0bJWUC+alFKNes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}