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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f51cfe64a7a5448a43b306ca7b928492956e6e04dab4e8d65e52939d3e17132' 
  AND token = 'MH/V0lE/SjbeBrgbCkkjVvVMDyuY0F8xuTiTFmwWwcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}