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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f17a5d052f2ab1f157ac56633de1b3d22f2d6fd7bcc6e471c72b21642e19c4' 
  AND token = 'tUBEWxwlH4RRVuUPoVUPRjETKhLfoaCmZxRN/XNPu1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}